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Related Experiment Videos

Hepatitis B surface antigen screening in a nonindigent population.

M C Meyer1, P B Mead, E L Capeless

  • 1Department of Obstetrics and Gynecology, University of Vermont, Burlington.

The Journal of Reproductive Medicine
|December 1, 1992
PubMed
Summary
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Universal screening for hepatitis B (HBsAg) in pregnant women may not be cost-efficient. Identifying high-risk patients effectively detected carriers in this privately funded population.

Area of Science:

  • Hepatology
  • Public Health
  • Obstetrics and Gynecology

Background:

  • Universal screening for hepatitis B surface antigen (HBsAg) in pregnant women is recommended.
  • Recommendations are often based on data from publicly funded healthcare settings.

Purpose of the Study:

  • To evaluate the cost-effectiveness of universal HBsAg screening in a predominantly privately funded population.
  • To determine if identifiable risk factors are sufficient for detecting HBsAg carriers in this demographic.

Main Methods:

  • Retrospective review of HBsAg screening results for 2,696 mothers delivering between May 1989 and April 1990.
  • Analysis of screening positivity rates and comparison with risk factor-based screening.

Main Results:

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  • The study population was 85% privately funded.
  • HBsAg screening was positive in 0.07% of mothers.
  • 19.6% of mothers did not have screening performed.
  • All positive cases could have been identified by targeting patients with known risk factors.

Conclusions:

  • Identifiable risk factors demonstrated high sensitivity for detecting HBsAg carriers in this population.
  • Universal HBsAg screening may not be a cost-efficient strategy for predominantly privately funded populations.
  • Further research may be needed to refine screening protocols based on population-specific data.