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Related Experiment Videos

[Hybridoma Data Bank (HDB)].

J Shimura1, S Miyazaki, H Sugawara

  • 1National Information System of Laboratory Organisms, Hybridoma Data Bank and World Data Center on Microorganisms, RIKEN.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 1, 1992
PubMed
Summary
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The Hybridoma Data Bank (HDB) offers over 23,000 monoclonal antibody records for research. This database provides comprehensive details and internet access, facilitating antibody data retrieval and analysis.

Area of Science:

  • Immunology
  • Biotechnology
  • Bioinformatics

Context:

  • The development of monoclonal antibodies (mAbs) has revolutionized biological research and diagnostics.
  • Managing and accessing the vast amount of data associated with mAbs presents a significant challenge.
  • International collaboration is crucial for creating comprehensive biological databases.

Purpose:

  • To introduce the Hybridoma Data Bank (HDB), a collaborative international database for monoclonal antibodies.
  • To detail the structure and content of the HDB, including antibody development, characteristics, and applications.
  • To explain the access procedures and interactive information retrieval systems available through the World Data Center (WDC) at RIKEN.

Summary:

  • The Hybridoma Data Bank (HDB) is an international collaborative effort by ATCC (USA), Cerdic (Europe), and RIKEN (Japan).

Related Experiment Videos

  • It contains over 23,000 records detailing monoclonal antibodies, including their development, isotype, specificity, applications, availability, and literature citations.
  • The World Data Center (WDC) at RIKEN provides internet-based access to the HDB, featuring an interactive information retrieval system and demonstrating data extraction for visual analysis.
  • Impact:

    • Provides a centralized, accessible resource for researchers worldwide studying monoclonal antibodies.
    • Facilitates efficient retrieval and utilization of mAb data, accelerating research and development.
    • Enables advanced data analysis, such as creating visual tables of antibody reactivity patterns, enhancing scientific discovery.