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Updated: Sep 22, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

[The connection between vitamin and antioxidant status of the children with decreased hemoglobin level]

V M Kodentsova, O A Vrzhesinskaia, N A Beketova

    Voprosy Pitaniia
    |July 23, 2003
    PubMed

    Insights

    Most children in Moscow had low hemoglobin and deficiencies in B vitamins and carotenoids. Higher vitamin B2 intake correlated with lower oxidative stress, suggesting its importance in treating iron deficiency anemia.

    Area of Science:

    • Nutritional Science
    • Biochemistry
    • Pediatrics

    Context:

    • Assessed vitamin status in 96 children (4-15 years) in Moscow with low hemoglobin (<120 g/l) during spring 2001.
    • Identified widespread deficiencies in B group vitamins and carotenoids, with vitamin C sufficiency.
    • Only 2% of children had adequate levels of all assessed vitamins.

    Purpose:

    • To investigate the vitamin sufficiency in children with decreased hemoglobin levels.
    • To explore correlations between specific vitamin levels and hemoglobin concentration.
    • To determine the role of vitamins, particularly B2, in lipid peroxidation.

    Summary:

    • 90% of children exhibited combined deficiencies in B vitamins and carotenoids.
    • A correlation was found between hemoglobin levels and serum concentrations of riboflavin and tocopherols.
    • A significant negative linear correlation was observed between riboflavin and malondialdehyde, indicating reduced oxidative stress with higher vitamin B2 levels.

    Impact:

    • Highlights the prevalence of multiple vitamin deficiencies in anemic children.
    • Provides evidence for the necessity of including vitamin B2 in the complex therapy for iron deficiency.
    • Suggests a potential therapeutic role for riboflavin in mitigating oxidative stress associated with anemia.

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