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Related Experiment Videos

Prostate localization using transabdominal ultrasound imaging.

Frieda Trichter1, Ronald D Ennis

  • 1Department of Radiation Oncology, Columbia University College of Physicians and Surgeons, New York, NY, USA. FTricher@sbhcs.com

International Journal of Radiation Oncology, Biology, Physics
|July 23, 2003
PubMed
Summary

The B-mode acquisition and targeting (BAT) system allows real-time prostate imaging, revealing significant prostate motion during treatment. This system may enable reduced tumor margins by accurately tracking prostate position compared to traditional methods.

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Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Diagnostic Imaging

Background:

  • Conventional prostate cancer treatment planning relies on static imaging, potentially leading to inaccuracies due to organ motion.
  • Margins are added around the prostate target to account for setup uncertainties and intra-treatment motion.
  • The B-mode acquisition and targeting (BAT) system offers real-time ultrasound imaging for prostate localization.

Purpose of the Study:

  • To compare prostate localization accuracy between the BAT system and conventional electronic portal imaging (EPI).
  • To analyze patient setup errors, BAT system reproducibility, and intra-fraction prostate motion.
  • To evaluate the impact of the BAT imaging procedure on prostate position.

Main Methods:

  • Daily isocenter shifts were calculated using both BAT and EPI for patients with localized prostate adenocarcinoma.

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  • Setup errors were compared, BAT reproducibility was assessed, and intra-fraction prostate motion was measured.
  • The effect of BAT imaging on prostate position was investigated by examining suprapubic pressure effects.

    • Main Results:

    • BAT identified significantly larger mean isocenter shifts (0.32-0.73 cm) due to prostate motion compared to EPI (0.01-0.24 cm).
    • BAT demonstrated good reproducibility, with 83-93% of shifts within acceptable limits (<0.2-0.3 cm).
    • Intra-fraction motion averaged 0.0-0.48 cm, and the BAT procedure induced minimal prostate motion (1 mm).

    Conclusions:

    • Prostate setup verification based on bony anatomy is insufficient for accurate targeting.
    • The BAT ultrasound system provides real-time prostate localization, enabling measurement of position variations.
    • BAT technology holds potential for reducing treatment margins in prostate cancer radiotherapy.