Retinal vessel changes in a patient with primary systemic nonfamilial amyloidosis

A case is described that demonstrates retinal vessel changes and suggests the favorable effects of hemodialysis to treat pathology in a patient with primary systemic nonfamilial amyloidosis. A 47-year-old woman diagnosed as having primary systemic nonfamilial amyloidosis at the age of 30 years had linear and dot hemorrhage, venous dilatation, and tortuosity in the right eye. Fluorescein angiography revealed low-density amorphous areas in the walls of dilated veins near the optic disc. These findings diminished with hemodialysis.