Candidal abscess of the parotid gland associated with facial nerve paralysis

Gino Marioni1, Roberto Rinaldi, Cosimo de Filippis

  • 1Department of Otolaryngology--Head and Neck Surgery, University of Padua, Padua, Italy. g_marioni@virgilio.it

Insights

Facial nerve paralysis from parotid gland infections is rare, often linked to bacteria. This study details the first case of facial nerve paralysis caused by a Candida albicans parotid abscess in a diabetic patient.

Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Neurology

Background:

  • Facial nerve paralysis typically arises from parotid gland tumors.
  • Parotid gland infections causing facial nerve dysfunction are exceptionally uncommon.
  • Literature review identified only about 15 prior cases of facial nerve palsy linked to suppurative parotitis or abscess.

Observation:

  • A 74-year-old insulin-dependent diabetic patient presented with facial nerve paralysis.
  • The patient was diagnosed with a candidal abscess of the parotid gland.
  • This represents the first reported instance of Candida albicans causing parotid abscess with associated facial nerve paralysis.

Findings:

  • Candida albicans can be an etiological agent in parotid gland abscesses.
  • Facial nerve paralysis can occur secondary to fungal parotid abscesses.
  • The case highlights an unusual presentation of facial nerve palsy.

Implications:

  • Diabetic and immunodeficient patients with parotid masses require broad differential diagnoses.
  • Candida albicans infection should be considered in the differential diagnosis of parotid abscesses presenting with facial nerve paralysis in at-risk populations.
  • This finding may influence diagnostic and treatment strategies for rare parotid gland infections.

Related Concept Videos

Cranial Nerves: Types Part I01:14

Cranial Nerves: Types Part I

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
Olfactory Nerve (Cranial Nerve I)
The olfactory nerve, or cranial nerve I, is unique as it is purely sensory and dedicated to the sense of smell. This nerve originates in the olfactory epithelium of the...
Botulism01:22

Botulism

Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...
Cranial Nerves: Types Part II01:22

Cranial Nerves: Types Part II

Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
Facial Nerve (Cranial Nerve VII)
Cranial nerve VII, or the facial nerve,...
Cranial Part of Parasympathetic Division01:18

Cranial Part of Parasympathetic Division

The cranial part of the parasympathetic division plays a crucial role in regulating the visceral functions of the head and specific structures in the neck, thoracic, and abdominopelvic cavities. Preganglionic fibers of the parasympathetic division exit the brain through cranial nerves III (oculomotor), VII (facial), IX (glossopharyngeal), and X (vagus), delivering parasympathetic output to the respective visceral structures.
The vagus nerve (cranial nerve X) alone accounts for approximately 75...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...