Related Experiment Video
Updated: Jul 3, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Acute headache as a presenting symptom of tacrolimus encephalopathy
I M Kiemeneij1, F-E de Leeuw, L M P Ramos
1Department of Neurology, University Medical Centre Utrecht, St Elisabeth Medical Centre Tilburg, Netherlands.
Abstract:
A 24 year old woman presented with a sudden excruciating headache mimicking an acute vascular event. She had undergone a lung transplantation because of cystic fibrosis and was receiving maintenance treatment with tacrolimus and prednisone. Ancillary investigation excluded vascular causes. Magnetic resonance imaging demonstrated hyperintense lesions in the infratentorial and parieto-occipital regions consistent with posterior leucencephalopathy syndrome. Both her clinical condition improved and the lesions disappeared completely after withdrawal of tacrolimus, suggesting that her condition could be explained by a tacrolimus encephalopathy.
Related Concept Videos
Cryptococcal Meningitis
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Brain Abscess l: Introduction
Increased Intracranial Pressure l: Introduction
Hepatic Encephalopathy

