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Published on: September 18, 2012
Spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis
1Institute of Clinical Neuroscience, Sahlgren's Academy of Göteborg University, Sahlgren's Hospital, S-413 45 Göteborg, Sweden. lars.frisen@neuro.gu.se
Objective:
To investigate the state of spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.
Methods:
Fifteen subjects suffering a first neurological episode suggestive of multiple sclerosis in clinical presentation, immunological profile, and magnetic resonance imaging, were examined with a new, sensitive test of spatial vision, rarebit perimetry. None had symptoms or signs of optic neuropathy.
Results:
Results of rarebit perimetry were significantly worse than those of 15 age matched normal controls (p=0.01); seven patients (47%) were outside normal limits. One patient only obtained abnormal results in high pass resolution perimetry.
Conclusions:
Rarebit perimetry may help to close the sensitivity gap between clinical examinations and neuroimaging.
