Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Keloid-like scleroderma.

Aviv Barzilai1, Anna Lyakhovitsky, Ada Horowitz

  • 1Department of Dermatology, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Israel. avivb@post.tau.ac.il

The American Journal of Dermatopathology
|July 24, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Insights and Prognostic Factors in Frontal Fibrosing Alopecia and Lichen Planopilaris: A Retrospective Cohort Study.

Dermatology (Basel, Switzerland)·2026
Same author

Pregnancy outcomes in patients with biologic-exposed psoriasis: A large cohort study of real-world safety.

Journal of the American Academy of Dermatology·2026
Same author

Efficacy of Topical Steroidal Treatment and Hand-Care Modification in Chronic Paronychia: A Retrospective Study.

Dermatology practical & conceptual·2026
Same author

From Onset to Outcome: A Long-term Retrospective, Single centre Study of Guttate Psoriasis from Israel.

Acta dermato-venereologica·2026
Same author

Efficacy of glucagon-like peptide 1 analogues in psoriasis: A cohort study.

JAAD international·2026
Same author

The MATRIX criteria: an internally validated scoring model for biopsy selection in longitudinal melanonychia.

The British journal of dermatology·2026
Same journal

Myxoid Variant of Primary Cutaneous Anaplastic Large Cell Lymphoma Mimicking Soft Tissue Sarcoma: Diagnostic Pitfalls and Literature Review.

The American Journal of dermatopathology·2026
Same journal

Herpetic Whitlow in Association With a Cutaneous Infiltrate of Chronic Lymphocytic Leukemia.

The American Journal of dermatopathology·2026
Same journal

Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.

The American Journal of dermatopathology·2026
Same journal

Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.

The American Journal of dermatopathology·2026
Same journal

On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.

The American Journal of dermatopathology·2026
Same journal

Montgomery Tubercles in the Male Areola: Histological Observations and a Brief About Past Investigators.

The American Journal of dermatopathology·2026
See all related articles

This study describes a rare case of keloidal scleroderma in a 62-year-old female, highlighting its scar-like histopathology. Accurate diagnosis requires careful clinical and pathological correlation for this scleroderma variant.

Area of Science:

  • Dermatology
  • Pathology
  • Rheumatology

Background:

  • Scleroderma is an autoimmune disease characterized by fibrosis.
  • Keloidal scleroderma is a rare variant presenting with keloid-like lesions.
  • Histological differentiation from typical keloids can be challenging.

Observation:

  • A 62-year-old female presented with acrosclerosis and keloid-like lesions.
  • Biopsies revealed dermal fibrous proliferation with horizontally oriented collagen bundles and myofibroblasts.
  • The histological findings mimicked scar tissue more than typical keloids.

Findings:

  • The patient's lesions were histopathologically indistinguishable from scars.
  • This presentation supports the designation of 'keloid-like scleroderma'.

Related Experiment Videos

  • This case is the first to demonstrate scar-like histopathology in this condition.

    • Implications:

    • Clinical pathological correlation is crucial for diagnosing keloid-like scleroderma.
    • This finding expands the understanding of scleroderma variants.
    • Accurate diagnosis impacts patient management and prognosis in scleroderma.