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Steady-state imaging for visualization of endovascular interventions
Alastair J Martin1, Oliver M Weber, Maythem Saeed
1Department of Radiology, University of California-San Francisco, San Francisco, California 94143, USA. Alastair.Martin@radiology.ucsf.edu
Magnetic Resonance in Medicine
|July 24, 2003
Summary
Steady-state MRI techniques can guide endovascular interventions. T(1)-shortening contrast agents improve device visualization by reducing artifacts and signal loss during procedures.
Area of Science:
- Magnetic Resonance Imaging (MRI)
- Medical Imaging
- Interventional Radiology
Background:
- Steady-state imaging techniques offer high spatial and temporal resolution for fluoroscopic applications.
- Disturbances in the steady state can lead to artifacts and reduced signal-to-noise ratio (SNR).
Purpose of the Study:
- To investigate the use of steady-state imaging for fluoroscopic MRI-guided endovascular interventions.
- To assess the impact of interventional devices on steady-state signals and explore mitigation strategies.
Main Methods:
- Examined how localized susceptibility defects in devices affect steady-state MRI signals in flowing blood.
- Evaluated the efficacy of T(1)-shortening contrast agents in reducing steady-state disturbances.
- Utilized an in vivo model with a dysprosium-marked catheter to assess visualization.
Main Results:
- Interventional devices with susceptibility defects significantly disturbed the steady-state signal, hindering device delineation in flow.
- T(1)-shortening contrast agents substantially reduced the time to achieve steady state, mitigating artifacts.
- A blood pool agent was essential for adequate in vivo visualization of the dysprosium-marked catheter.
Conclusions:
- Steady-state MRI shows promise for fluoroscopic guidance in endovascular procedures.
- T(1)-shortening contrast agents and blood pool agents are crucial for overcoming signal disturbances and enhancing device visualization.