Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Indications for continuous renal function replacement therapy].

Petar Kes1, Dragan Ljutić, Nikolina Basić-Jukić

  • 1Zavod za dijalizu, Klinicki bolnicki centar Zagreb, Kispatićeva 12 10000 Zagreb, Hrvatska.

Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti
|July 25, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Qualified prediction system for allograft failure in real world settings: extended validation study.

BMJ medicine·2026
Same author

Long-Term Outcome of Kidney Transplant Patients from Rural Farming Areas with Balkan Nephropathy-A Single-Centre Report.

Journal of clinical medicine·2026
Same author

Post-Transplant Sepsis After Liver Transplantation: Clinical Characteristics and Therapeutic Challenges.

Journal of clinical medicine·2026
Same author

Uremic Pruritus in Hemodialysis: Mechanisms, Burden, and Emerging Therapies.

Journal of clinical medicine·2026
Same author

Exploring Perspectives on Kidney Donation: Medical and Non-Medical Students in Croatia.

Journal of clinical medicine·2026
Same author

Impact of the COVID-19 pandemic on university performance: a retrospective follow-up study of the University of Split, Croatia.

Journal of global health·2026

Continuous renal replacement therapy (CRRT) is a vital intensive care treatment for acute kidney injury and other critical conditions. CRRT effectively removes inflammatory mediators, improving hemodynamic stability and organ function in critically ill patients.

Area of Science:

  • Critical Care Medicine
  • Nephrology
  • Intensive Care Management

Context:

  • Continuous renal replacement therapy (CRRT) is a cornerstone of modern intensive care, addressing acute kidney injury (AKI) and its complications.
  • Indications range from acute renal failure with heart failure and volume overload to systemic inflammatory response syndrome (SIRS), sepsis, and multiorgan failure (MOF).
  • CRRT is employed in perioperative settings, including post-cardiac surgery and transplantation, and its early initiation aims to prevent organ damage.

Purpose:

  • To summarize the indications, methods, and therapeutic benefits of CRRT in intensive care.
  • To highlight CRRT's role in managing sepsis, SIRS, and MOF by removing inflammatory mediators.
  • To discuss the controversial prophylactic use of CRRT and its risk-benefit profile.

Summary:

Related Experiment Videos

  • CRRT is indicated for acute renal failure, heart failure, liver failure, brain swelling, SIRS, sepsis, and MOF.
  • Studies show CRRT removes inflammatory substances like cytokines, improving hemodynamic stability and gas exchange.
  • While prophylactic CRRT is debated, its use is justified in patients with MOF signs, sepsis, or risk of organ failure.

Impact:

  • CRRT significantly improves outcomes in critically ill patients by mitigating organ dysfunction and inflammation.
  • The therapy offers benefits beyond fluid and electrolyte balance, including removal of inflammatory mediators.
  • Further research is needed to clarify the role of prophylactic CRRT, balancing its benefits against potential risks.