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Updated: Sep 21, 2026

Analysis of Oxidative Stress in Zebrafish Embryos
Published on: July 7, 2014
[Oxidative stress]
1Health Service Center, University of Tokyo.
Abstract:
Oxidative stress, which is enhanced in diabetes mellitus, causes hypertension and plays a critical role on cardiovascular damages in diabetes and hypertension. Angiotensin II is one of important intrinsic oxidants in pathophysiology of hypertension. Reactive oxygen species affect hypertension and its complications via inactivation of nitric oxide, modification of lipid metabolism, and enhanced insulin resistance. Moreover, oxidative stress and hypertension accelerate cardiovascular damages. Thus, it is important to control oxidative stress in hypertensive patients with diabetes.
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