Related Experiment Video
Updated: Jun 24, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 5, 2010
Overcoming childhood asthma disparities of the inner-city poor
Monica J Federico1, Andrew H Liu
1Division of Pediatric Pulmonary, The Children's Hospital, 1056 East 19th Avenue, Denver, CO 80262 USA. jonesmo@NJC.org
Insights
Children in low-income urban communities face severe asthma burdens, including frequent hospitalizations and deaths. Research is exploring environmental, biologic, and management factors to reduce these health disparities.
Area of Science:
- Environmental Health
- Pediatric Asthma Research
- Health Disparities
Background:
- Inner-city children in low-income families experience disproportionately high rates of severe asthma outcomes.
- Factors contributing to these poor outcomes include environmental exposures, biologic elements, and inadequate disease management.
Purpose of the Study:
- To investigate the multifaceted factors contributing to severe asthma in urban children.
- To identify strategies for optimizing and implementing interventions to reduce asthma-related disparities and costs.
Main Methods:
- Ongoing multifaceted studies are examining the complex interplay of factors leading to severe asthma.
- Research focuses on understanding environmental triggers, biologic predispositions, and disease management practices.
Main Results:
- Severe asthma disproportionately affects children in low-income, inner-city communities.
- A combination of environmental, biologic, and mismanagement factors contributes to poor asthma outcomes.
Conclusions:
- Optimizing and broadly implementing interventions are crucial to mitigate severe asthma consequences.
- Efforts aim to narrow outcome disparities and reduce healthcare expenditures for pediatric asthma.
Abstract:
Asthmatic children living in low-income families in United States inner city communities continue to have disproportionately high rates of hospitalizations, emergency department visits, disability, and death. Current research implicates a combination of environmental, biologic, and disease mismanagement factors that underlie these poor outcomes. Multifaceted studies are underway to better understand this inner-city path to severe asthma. Efforts to optimize interventions, to implement them broadly, and to sustain them are also underway on local and national levels. It is hoped that these efforts will limit the severe consequences of asthma, narrow disparities in outcomes, and substantially reduce medical expenditures for asthma.
Related Concept Videos
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction
Asthma-III: Symptoms and Complications
Classification of Asthma
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Asthma III: Clinical Manifestations

