Methylated DNA as a possible screening marker for neoplastic disease in several body fluids
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Updated: Sep 20, 2026
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Methyl-binding DNA capture Sequencing for Patient Tissues
Published on: October 31, 2016
Hannes M Müller1, Martin Widschwendter
1Department of Obstetrics and Gynecology, Innsbruck University Hospital, Austria. Hannes.Mueller@uibk.ac.at
Expert Review of Molecular Diagnostics
|July 25, 2003
Abstract:
Early detection appears to be one of the most important approaches to reducing mortality caused by neoplasia. Changes in DNA methylation have been recognized as one of the most common molecular alterations in human tumors. Due to the ubiquity of DNA methylation changes and the possibility to detect methylated DNA in several body fluids, this specifically altered DNA may serve as a potential new screening marker for neoplastic disease.
