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Lesson of the month. The value of immunohistochemistry in breast pathology

H J Sidebotham1, R K Al-Talib, J M Theaker

  • 1Southampton General Hospital and Royal Hampshire County Hospital, UK.

Histopathology
|July 25, 2003
PubMed
Abstract

No abstract available in PubMed .

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Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
These...