Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Flavanoids from Caesalpinia pulcherrima.

K V N S Srinivas1, Y Koteswara Rao, I Mahender

  • 1Indian Institute of Chemical Technology, Hyderabad-500 007, India.

Phytochemistry
|July 25, 2003
PubMed
Summary

Researchers isolated novel flavanoids from Caesalpinia pulcherrima, including 5,7-dimethoxy-3

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Design, synthesis, and biological evaluation of vanillin-piperidone hybrids with potent anticancer activity and a favourable genotoxic profile.

RSC advances·2026
Same author

Retraction notice to "Synthesis and antidepressant-like effects of new 5-epi-incensole and 5-epi- incensole acetate in chronic unpredictable mild stress model of depression; behavioural and biochemical correlates" [Biomedicine & Pharmacotherapy 156 (2022) 113960].

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

From CO<sub>2</sub> to C<sub>1</sub> Liquid Fuels: Molecular Electrochemical Production of Formic Acid and Methanol.

Angewandte Chemie (International ed. in English)·2025
Same author

Design, synthesis, and <i>in silico</i> docking studies of novel cinnamaldehyde-chalcone derivatives with anti-cancer potential and <i>in vivo</i> acute oral toxicity profiling.

RSC advances·2025
Same author

More bang for your buck: potential gains through optimizing maize breeding schemes in sub-Saharan Africa.

Frontiers in plant science·2025
Same author

Molecularly Designed Cathode for Copper-Benzimidazole-Induced CO<sub>2</sub> Reduction to MeOH.

Angewandte Chemie (International ed. in English)·2025

Area of Science:

  • Phytochemistry
  • Natural Product Chemistry
  • Organic Chemistry

Background:

  • Caesalpinia pulcherrima is a plant species known for its diverse chemical constituents.
  • Flavanoids and chalcones are classes of natural products with a wide range of biological activities.
  • Isolation and structural elucidation of novel compounds contribute to understanding plant-based medicinal resources.

Purpose of the Study:

  • To isolate and characterize new flavanoid compounds from the aerial parts of Caesalpinia pulcherrima.
  • To determine the chemical structures of the isolated compounds using spectroscopic methods.
  • To evaluate the antimicrobial potential of the newly identified compounds.

Main Methods:

  • Extraction of compounds from the aerial parts of Caesalpinia pulcherrima.
  • Purification of isolated compounds using chromatographic techniques.
  • Structural elucidation utilizing 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy.
  • Assessment of antimicrobial activity of the novel compounds.

Main Results:

  • Two new flavanoids, 5,7-dimethoxy-3',4'-methylenedioxyflavanone and isobonducellin, were successfully isolated.
  • Additional known compounds, 2'-hydroxy-2,3,4',6'-tetramethoxychalcone, 5,7-dimethoxyflavone, and bonducellin, were also identified.
  • The structure of isobonducellin was confirmed as a homoisoflavanoid with a cis (Z)-double bond.
  • The antimicrobial activity of the new compounds was evaluated.

Conclusions:

  • The study successfully identified and characterized novel flavanoids from Caesalpinia pulcherrima.
  • The structural analysis confirmed the presence of unique chemical scaffolds.
  • The isolated compounds show potential for further investigation into their biological properties, particularly antimicrobial activity.

Related Experiment Videos