Reprogramming cells for transplantation

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Updated: Sep 21, 2026

Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program
11:00

Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program

Published on: December 16, 2016

Jonathan Leor1, Alexander Battler, Robert A Kloner

  • 1Neufeld Cardiac Research Institute, Sheba Medical Center, Tel-Hashomer, Israel. leorj@post.tau.ac.il

Heart Failure Reviews
|July 25, 2003
PubMed

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Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
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