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Updated: Sep 21, 2026

Antibody Profiling by Luciferase Immunoprecipitation Systems (LIPS)
Published on: October 7, 2009
Antiphospholipid antibodies and the antiphospholipid antibody syndrome
1Department of Dermatology, Saint Louis University School of Medicine, Saint Louis, Missouri 63104, USA.
Abstract:
The antiphospholipid antibody syndrome is a multisystem disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia and recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this disorder. Various hematologic, neurologic, obstetric and cutaneous abnormalities are manifest in this syndrome. This article reviews the characteristic features of the antiphospholipid antibody syndrome.
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