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Updated: Aug 8, 2026

Longitudinal Evaluation of Mouse Hind Limb Bone Loss After Spinal Cord Injury using Novel, in vivo, Methodology
Published on: December 7, 2011
Congenital longitudinal deficiency of the tibia
D A Spiegel1, R T Loder, R C Crandall
1Shriners Hospitals for Children/Twin Cities, 2025 East River Parkway, Minneapolis, MN 55414, USA. dspiegel@shrinenet.org
Abstract:
We performed a clinical and radiographic review of 15 patients (19 limbs) with longitudinal deficiency of the tibia treated between 1981 and 2001. Ten limbs with Kalamchi type I deficiencies were managed by through-knee amputation. Five type II deficiencies were treated by foot ablation and tibiofibular synostosis, either at the same time or staged, but prosthetic problems may arise from varus alignment and prominence of the proximal fibula. Patients with type III deficiencies (four cases) were treated by foot ablation. Prosthetic problems relating to proximal or distal tibiofibular instability may necessitate additional surgical intervention.
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