Related Experiment Video
Updated: Jul 18, 2026

05:30
Cercarial Transformation and in vitro Cultivation of Schistosoma mansoni Schistosomules
Published on: August 16, 2011
Cost analysis of schistosomiasis
1Wellcome Trust Research Centre for Parasitic Infections, Imperial College, London, UK.
Transactions of the Royal Society of Tropical Medicine and Hygiene
|November 1, 1992
Summary
Understanding the economic impact of schistosomiasis is crucial for effective disease control strategies. Further research needs to incorporate realistic dynamics for accurate cost-effectiveness analysis of schistosomiasis interventions.
Area of Science:
- Public Health
- Health Economics
- Epidemiology
Background:
- Cost analysis of schistosomiasis is vital for assessing its economic burden and guiding control strategies.
- Previous economic impact assessments have focused on the health sector, neglecting broader effects on production and community development.
- Existing cost-effectiveness analyses of control methods often rely on empirical data and static models.
Purpose of the Study:
- To highlight the importance of comprehensive cost analysis for schistosomiasis.
- To identify gaps in current economic impact assessments, particularly concerning non-health sector effects.
- To advocate for improved methodologies in cost-effectiveness research for schistosomiasis control.
Main Methods:
- Review of existing literature on schistosomiasis cost analysis and economic impact.
- Identification of limitations in current epidemiological and economic modeling approaches.
- Conceptual framework for future research incorporating disease dynamics and broader economic impacts.
Main Results:
- Economic impact assessments often lack measurement of effects on production and community development.
- Current cost-effectiveness studies may not fully capture the long-term economic consequences of schistosomiasis.
- There is a need for more robust epidemiological data and dynamic modeling.
Conclusions:
- Accurate cost analysis of schistosomiasis requires consideration of both direct and indirect economic impacts.
- Future research should integrate realistic demographic and epidemiological data, including reinfection dynamics.
- Evaluating control strategies based on disease outcomes, not just infection prevalence, is essential for accurate cost-effectiveness.
Related Concept Videos
Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Malaria
Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Giardiasis
Giardiasis is a globally prevalent intestinal infection caused by the protozoan parasite Giardia duodenalis (also known as G. lamblia or G. intestinalis). This flagellated protozoan is the most frequently identified intestinal parasite in the United States and worldwide. Transmission primarily occurs via the fecal-oral route, with infection arising from ingestion of water or food contaminated with cysts. Individuals in low-resource settings, international travelers, outdoor enthusiasts, daycare...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Anthelminthic Agents
Anthelmintic drugs differ significantly from antiparasitic therapies targeting protozoa, primarily due to differences in parasite biology. Whereas most protozoal treatments act on proliferating cells, anthelmintics are typically directed against mature, nonproliferative helminths. The therapeutic approach considers the helminth's reliance on neuromuscular coordination, glucose metabolism, and microtubular integrity for survival, reproduction, and localization within the host. Most anthelmintics...

