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Ventricular dilatations.

Catherine Garel1, Dominique Luton, Jean-François Oury

  • 1Department of Paediatric Imaging, Robert Debré Hospital, 48 boulevard Sérurier, 75019 Paris, France. catherine.garel@rdb.ap-hop-paris.fr

Child'S Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery
|July 25, 2003
PubMed
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Fetal ventriculomegaly, or enlarged ventricles, has a debated prognosis. Isolated, stable cases generally have a good outlook, while those with associated anomalies or genetic issues suggest a poorer outcome.

Area of Science:

  • Prenatal diagnosis
  • Fetal imaging
  • Neurology

Background:

  • Ventricular dilatation is defined as ventricles larger than 10-12 mm on ultrasound or MRI after 22 weeks gestation.
  • This measurement is independent of gestational age after 22 weeks.

Purpose of the Study:

  • To emphasize the importance of assessing ventricular dilatation progression for prognostication.
  • To highlight the need for comprehensive evaluation of associated anomalies and fetal status.

Main Methods:

  • Utilizing ultrasound (US) and magnetic resonance imaging (MRI) for ventricular measurement.
  • Assessing ventricular lining, content, associated brain malformations, and other fetal parameters (biparietal diameter, head circumference, subarachnoid width).
  • Recommending karyotype analysis, fetal infection screening, and evaluation for extracranial malformations.

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Main Results:

  • Prognosis is debated and depends heavily on associated findings.
  • Poor prognosis is linked to malformations, brain insult, tri-/tetraventricular enlargement, and karyotype anomalies.
  • Good prognosis is associated with isolated, biventricular, stable, or regressive ventriculomegaly.

Conclusions:

  • The relationship between ventricular size and unilateral/bilateral dilatation remains under discussion.
  • Comprehensive prenatal evaluation is crucial for determining the prognosis of fetal ventriculomegaly.