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Published on: October 12, 2018

Congenital HIV infection and precocious puberty

James M Horner1, Nasreen A Bhumbra

  • 1Department of Pediatrics, Division of Endocrinology, Medical College of Ohio, Mercy Children's Hospital, Toledo, OH 43608, USA. jhorner@mco.edu

Journal of Pediatric Endocrinology & Metabolism : JPEM
|July 26, 2003
PubMed

Insights

Precocious puberty is a rare endocrine complication in children with human immunodeficiency virus (HIV) infection. This case highlights an unusual presentation of early puberty in a child with congenital HIV.

Area of Science:

  • Pediatric Endocrinology
  • Infectious Diseases
  • Human Immunodeficiency Virus (HIV) Research

Background:

  • Endocrine complications in children with HIV infection typically include growth deceleration and delayed puberty.
  • Understanding the spectrum of endocrine manifestations in pediatric HIV is crucial for comprehensive patient care.

Observation:

  • A case report of an African-American male with congenital human immunodeficiency virus (HIV) infection is presented.
  • The patient was diagnosed with precocious puberty at 4 years and 9 months of age.

Findings:

  • This case presents an atypical endocrine manifestation of HIV infection in a pediatric patient.
  • Precocious puberty, rather than delayed development, was observed in this child with congenital HIV.

Implications:

  • This case expands the known endocrine complications associated with pediatric HIV infection.
  • Further research may be needed to understand the mechanisms underlying precocious puberty in HIV-infected children.

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