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[Severe acute respiratory syndrome].

Mao-de Lai1, Yi-min Zhu, Xue-mei Gu

  • 1Department of Pathology, College of Medical Sciences, Zhejiang University, Hangzhou 310031, China.

Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences
|July 26, 2003
PubMed
Summary

Severe acute respiratory syndrome (SARS), caused by SARS-associated coronavirus (SCV), is a severe infectious disease. Pathologically, it involves lung inflammation and can affect other organs, with diagnosis evolving as understanding grows.

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Area of Science:

  • Infectious Diseases
  • Virology
  • Pathology

Context:

  • First identified severe infectious disease of the 21st century.
  • Caused by the SARS-associated coronavirus (SCV).

Purpose:

  • To describe the pathological characteristics of SARS.
  • To outline the clinical diagnostic process for SARS.
  • To recommend the Chinese term for SARS.

Summary:

  • Pathological findings include interstitial exudative inflammation and hyaline membrane formation in the lungs during the acute phase.
  • Extrapulmonary organs may exhibit hemorrhagic inflammation.
  • Clinical diagnosis is a dynamic process, progressing through suspected, probable, and definite case classifications.

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Impact:

  • Provides a foundational understanding of SARS pathology and clinical diagnosis.
  • Highlights the evolving nature of diagnostic standards for emerging infectious diseases.
  • Contributes to standardized terminology for SARS in Chinese.