Use of ionic liquids in a lipase-facilitated supported liquid membrane
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Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
Published on: July 10, 2016
Eijiro Miyako1, Tatsuo Maruyama, Noriho Kamiya
1Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, 6-10-1 Hakozaki, Fukuoka 812-8581, Japan.
Abstract:
A lipase-facilitated transport of 4-phenoxybutyric acid, 3-phenoxypropionic acid, 2-phenylpropionic acid, 2-phenoxybutyric acid, mandelic acid and 2-amino-2-phenylbutyric acid was carried out using a supported liquid membrane based on room temperature ionic liquids. There were marked differences in the permeate fluxes of various organic acids due to the substrate specificity of the lipases. The maximum permeate flux (44 x 10(-2) mmol cm-2 x h) was obtained using 4-phenoxybutyric acid as the substrate and 1-n-butyl-3-methylimidazolium hexafluorophosphate as the liquid membrane phase.
