A novel cross-linking reagent for bovine hemoglobin modification
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Minglei He1, Xiuling Lu, Dongxu Zhao
1National Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box. 353, Beijing 100080, PR China.
Biotechnology Letters
|July 29, 2003
Abstract:
A novel cross-linking reagent, methoxypolyethelene glycol-glutamic acid, was synthesized and used to modify bovine hemoglobin. Bis-tetrameric hemoglobin with moderate affinity for O2 was obtained under the controlled reaction conditions.
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