Related Experiment Video

Updated: Sep 21, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

[Long-term results of mitral-aortic valve replacement in 1,154 patients with rheumatic valvular disease]

Bao-ren Zhang1, Liang-jian Zou, Zhi-yun Xu

  • 1Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.

Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|July 29, 2003
PubMed

Insights

This study on mitral-aortic valve replacement for rheumatic valvular disease shows improved survival and reduced complications. Optimal anticoagulant therapy and tricuspid valve repair are key for better patient outcomes.

Area of Science:

  • Cardiovascular Surgery
  • Rheumatic Heart Disease
  • Valvular Heart Disease

Context:

  • Rheumatic valvular disease frequently impairs both left and right ventricular function.
  • Combined mitral-aortic valve replacement is a critical intervention for severe rheumatic valvular disease.
  • Patients often present with advanced New York Heart Association functional class (III/IV) and pulmonary hypertension.

Purpose:

  • To evaluate the early and long-term outcomes of combined mitral-aortic valve replacement in rheumatic valvular disease.
  • To identify determinant factors influencing outcomes.
  • To assess subsequent therapeutic strategies.

Summary:

  • A review of 1154 patients undergoing mitral-aortic valve replacement for rheumatic valvular disease between 1981 and 2001.
  • Hospital mortality decreased, with 5-, 10-, and 15-year survival rates of 89.46%, 86.50%, and 67.86% respectively.
  • High rates of freedom from thromboembolic events (97.80% at 5 years) and anticoagulant-related bleeding (94.80% at 5 years) were observed, with significant functional status improvement.

Impact:

  • Highlights the importance of exploring the tricuspid valve during surgery and correcting significant lesions.
  • Recommends long-acting penicillin for rheumatic fever relapse prevention.
  • Suggests a low-intensity anticoagulant regimen (PT 1.5-2.0) to balance bleeding and thromboembolic risk.
Abstract

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
Mitral Regurgitation II: Clinical Features and Diagnostic Tests01:23

Mitral Regurgitation II: Clinical Features and Diagnostic Tests

Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...