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[Prevalence of metabolic syndrome in patients with coronary heart disease]

Antonio Hernández Mijares1, Concepción Riera Fortuny, Eva Solá Izquierdo

  • 1Sección de Endocrinología. Hospital Universitario Dr. Peset. Valencia. Spain. hernandez_antmij@gva.es

Medicina Clinica
|July 29, 2003
PubMed

Insights

Patients with coronary heart disease (CHD) have significantly higher rates of cardiovascular risk factors, insulin resistance, and metabolic syndrome (MS). These findings highlight a strong association between MS and CHD, even with treatment.

Area of Science:

  • Cardiology
  • Endocrinology
  • Metabolic Health

Background:

  • Coronary heart disease (CHD) is a major health concern.
  • Understanding associated metabolic risk factors is crucial for prevention and management.

Purpose of the Study:

  • To determine the prevalence of cardiovascular risk factors, hyperinsulinism, insulin resistance, and metabolic syndrome (MS) in patients with CHD.
  • To compare these factors with a control group without a history of cardiovascular disease.

Main Methods:

  • An observational, transversal study involving 367 adults (35-79 years).
  • 185 patients with CHD and 182 controls were analyzed.
  • Insulin resistance was assessed using the Homeostasis Model Assessment (HOMA) index.

Main Results:

  • CHD patients exhibited higher blood pressure, BMI, triglycerides, and apo B100, with lower HDL-c and apo A1 compared to controls.
  • Higher glycemia, insulinemia, and HOMA index were observed in the CHD group.
  • Prevalence in CHD population: 38.28% hyperinsulinism, 47.02% insulin resistance (HOMA), and 41.08% MS.

Conclusions:

  • A high prevalence of cardiovascular risk factors, hyperinsulinism, insulin resistance, and MS exists in the CHD population.
  • A clear association between MS and CHD is evident in both men and women, persisting despite treatment.
Abstract

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