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A program for managing weight gain associated with atypical antipsychotics.

Betty Vreeland1, Shula Minsky, Matthew Menza

  • 1Department of Psychiatry-Robert Wood Johnson Medical School and University Behavioral Health Care, University of Medicine and Dentistry of New Jersey, Piscataway, 08855, USA. vreelael@umdnj.edu

Psychiatric Services (Washington, D.C.)
|July 29, 2003
PubMed
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A weight control program significantly reduced weight and BMI in patients taking atypical antipsychotics. This intervention, including nutrition and exercise, offers a viable strategy for managing medication side effects.

Area of Science:

  • Psychiatry
  • Metabolic Health
  • Clinical Nutrition

Background:

  • Atypical antipsychotics are associated with significant weight gain and metabolic disturbances.
  • Managing weight gain is crucial for the long-term health and treatment adherence of patients with schizophrenia or schizoaffective disorder.

Purpose of the Study:

  • To evaluate the effectiveness of a 12-week multidisciplinary weight control program for patients on atypical antipsychotics.
  • To assess the impact of nutrition, exercise, and behavioral interventions on weight and Body Mass Index (BMI) in this patient population.

Main Methods:

  • A 12-week intervention study involving 31 patients receiving atypical antipsychotics.
  • Participants engaged in a program combining nutritional counseling, physical activity, and behavioral strategies.

Related Experiment Videos

  • A control group of 15 patients receiving standard care was used for comparison.

    • Main Results:

    • The intervention group achieved a mean weight loss of 2.7 kg (6 pounds) and a mean BMI reduction of 0.98 points.
    • The control group experienced a mean weight gain of 2.9 kg (6.4 pounds) and a mean BMI increase of 1.2 points.
    • Statistical significance was implied by the contrasting outcomes between groups.

    Conclusions:

    • The weight control program demonstrated efficacy in mitigating weight gain and reducing BMI in patients taking atypical antipsychotics.
    • Healthcare professionals should recommend weight management interventions for patients on these medications.
    • Lifestyle interventions are a valuable tool in managing the metabolic side effects of atypical antipsychotic therapy.