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Related Experiment Videos

Non-linear material models for tracheal smooth muscle tissue.

P A Sarma1, R M Pidaparti, P N Moulik

  • 1Department of Mechanical Engineering, Purdue School of Engineering and Technology, IUPUI, Indianapolis, IN 46202, USA.

Bio-Medical Materials and Engineering
|July 29, 2003
PubMed
Summary

The Ogden material model accurately describes tracheal smooth muscle tissue

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Area of Science:

  • Biomedical Engineering
  • Computational Mechanics
  • Tissue Mechanics

Background:

  • Tracheal smooth muscle exhibits complex non-linear stress-strain behavior.
  • Accurate material models are crucial for understanding tissue mechanics and disease.
  • Existing models may not fully capture the unique properties of tracheal smooth muscle.

Purpose of the Study:

  • To investigate hyperelastic material models for tracheal smooth muscle.
  • To validate material models using experimental data and finite element analysis.
  • To analyze stress-strain behavior trends in smooth muscle tissue.

Main Methods:

  • Development and application of hyperelastic material models.
  • Utilizing 2D and 3D finite element analyses.

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  • Validation against experimental stress-strain data.

    • Main Results:

    • The Ogden material model demonstrated validity and utility.
    • The model effectively explains stress-strain behavior under various conditions.
    • Finite element simulations provided insights into transverse stress-strain responses.

    Conclusions:

    • The Ogden model is a suitable tool for simulating tracheal smooth muscle.
    • This research enhances the understanding of airway smooth muscle mechanics.
    • Finite element analysis aids in validating constitutive models for biological tissues.