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The use of infliximab in cutaneous sarcoidosis
1Department of Internal Medicine, Sections of Dermatology and Pulmonary and Critical Care Medicine, Walter Reed Army Medical Center, 4515 Willard Avenue #1018, Chevy Chase, MD 20815, USA. jon.meyerle@verizon.net
Abstract:
Infliximab, a chimeric (humanized mouse) monoclonal antibody which specifically inhibits TNF-alpha, has recently shown efficacy in the treatment of refractory sarcoidosis. The manifestations of sarcoidosis are diverse; however, the long-term effects on the lungs are often the most life-threatening. We describe a patient with sarcoidosis who experienced the complete resolution of her cutaneous disease and stabilization of her pulmonary symptoms after initiation of infliximab.
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