Venous thromboembolic disease: comparison of the diagnostic process in men and women

Paul D Stein1, Russell D Hull, Kalpesh C Patel

  • 1Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA. steinp@trinity-health.org

Insights

This study found no evidence of sex bias in the diagnosis or treatment of pulmonary embolism (PE) or deep venous thrombosis (DVT). Diagnostic test utilization and hospitalization durations were similar for men and women.

Area of Science:

  • Medical research
  • Clinical diagnostics
  • Public health

Background:

  • Concerns exist regarding potential sex disparities in diagnostic test access for women.
  • It remains undetermined if these disparities affect patients with pulmonary embolism (PE) or deep venous thrombosis (DVT).

Purpose of the Study:

  • To investigate potential sex-based differences in diagnostic test application for PE and DVT.
  • To examine sex disparities in diagnosis, medical facility utilization, and treatment duration for PE and DVT.

Main Methods:

  • Utilized cross-sectional data from the National Hospital Discharge Survey (1979-1999).
  • Analyzed inpatient records from noninstitutional hospitals across the United States.
  • Employed International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify PE, DVT, and diagnostic procedures.

Main Results:

  • Age-adjusted diagnosis rates for PE and DVT were comparable between sexes.
  • Utilization rates for ventilation-perfusion lung scans, venous ultrasonography, and contrast venography were not lower in women.
  • Hospitalization durations for PE or DVT showed no significant difference between men and women.

Conclusions:

  • National Hospital Discharge Survey data do not support a sex bias in PE or DVT diagnosis.
  • Evidence does not indicate sex disparities in the use of diagnostic tests for PE or DVT.
  • Hospitalization durations for PE and DVT are comparable across sexes, refuting claims of bias.
Abstract

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...