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Updated: Sep 20, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Venous thromboembolic disease: comparison of the diagnostic process in men and women
Paul D Stein1, Russell D Hull, Kalpesh C Patel
1Department of Research, St Joseph Mercy Oakland Hospital, Pontiac, Michigan, USA. steinp@trinity-health.org
Insights
This study found no evidence of sex bias in the diagnosis or treatment of pulmonary embolism (PE) or deep venous thrombosis (DVT). Diagnostic test utilization and hospitalization durations were similar for men and women.
Area of Science:
- Medical research
- Clinical diagnostics
- Public health
Background:
- Concerns exist regarding potential sex disparities in diagnostic test access for women.
- It remains undetermined if these disparities affect patients with pulmonary embolism (PE) or deep venous thrombosis (DVT).
Purpose of the Study:
- To investigate potential sex-based differences in diagnostic test application for PE and DVT.
- To examine sex disparities in diagnosis, medical facility utilization, and treatment duration for PE and DVT.
Main Methods:
- Utilized cross-sectional data from the National Hospital Discharge Survey (1979-1999).
- Analyzed inpatient records from noninstitutional hospitals across the United States.
- Employed International Classification of Diseases, Ninth Revision, Clinical Modification codes to identify PE, DVT, and diagnostic procedures.
Main Results:
- Age-adjusted diagnosis rates for PE and DVT were comparable between sexes.
- Utilization rates for ventilation-perfusion lung scans, venous ultrasonography, and contrast venography were not lower in women.
- Hospitalization durations for PE or DVT showed no significant difference between men and women.
Conclusions:
- National Hospital Discharge Survey data do not support a sex bias in PE or DVT diagnosis.
- Evidence does not indicate sex disparities in the use of diagnostic tests for PE or DVT.
- Hospitalization durations for PE and DVT are comparable across sexes, refuting claims of bias.
Background:
There has been concern that women may be limited to fewer major diagnostic tests than men. Whether this applies to patients with pulmonary embolism (PE) or deep venous thrombosis (DVT) has not been determined.
Objective:
To assess whether there is a sex disparity in the application of diagnostic tests for PE or DVT, in reaching a diagnosis, or in using medical facilities.
Design:
A study of cross-sectional samples of hospitalizations from 21 separate years using data from the National Hospital Discharge Survey.
Setting:
Noninstitutional hospitals in the 50 states and the District of Columbia from 1979 through 1999.
Patients:
The National Hospital Discharge Survey abstracts demographic and medical information from the medical records of inpatients. For 1979 through 1999, the number of patients sampled ranged from 181000 to 307000.Measurements The number of sampled patients with DVT and with PE and the number of diagnostic tests performed were determined from the International Classification of Diseases, Ninth Revision, Clinical Modification codes at discharge. A multistage estimation procedure gave an estimation of values for the entire United States.
Results:
Age-adjusted rates of the diagnosis of PE per 100000 population and of DVT per 100000 population were not lower in women. Rates of the use of ventilation-perfusion lung scans, venous ultrasonography of the lower extremities, and contrast venography were not lower in women. Durations of hospitalization for PE or DVT were comparable in men and women.
Conclusion:
Data from the National Hospital Discharge Survey do not support a sex bias in the diagnosis of PE or DVT, the use of diagnostic tests, or the duration of hospitalization for PE or DVT.
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