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[Unconventional culture of the human hepatitis B virus (HBV)]
1Institut de Virologie, Stefan S. Nicolau, Bucarest, Roumanie.
Abstract:
The investigation of the key stages of the HBV vital cycle was realised recently through an unconventional cultivation technique, using transfection with an adequate DNA, cloned in plasmids. Transfections was achieved in cell lines, differentiated or not. The results showed that expression of some of the HBV genes is under the control of hepatospecific factors.