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Updated: Sep 20, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
[Indications of coronary cineangiography in coronary heart disease]
Maria Cecilia Solimene1, José Antonio Franchini Ramires
1Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, S. Paulo, SP, Brasil.
Insights
Coronary arteriography is increasingly used for coronary heart disease, especially for acute coronary syndromes. Indications are clarified, guiding its use in high-risk patients while non-invasive tests suit low-risk individuals.
Area of Science:
- Cardiology
- Interventional Cardiology
- Diagnostic Imaging
Background:
- Advances in myocardial revascularization and interventions favor invasive strategies for coronary heart disease.
- Coronary arteriography is now more frequently indicated due to technological improvements.
- Acute coronary syndromes, including non-ST-segment elevation myocardial infarction and unstable angina, share unified management guidelines.
Purpose of the Study:
- To review and clarify the indications for coronary arteriography in managing coronary heart disease.
- To discuss the role of coronary arteriography in the diagnosis and prognosis of coronary heart disease.
- To differentiate appropriate use cases from situations where non-invasive testing is preferred.
Main Methods:
- Review of current medical literature and clinical guidelines.
- Analysis of diagnostic and prognostic indications for coronary arteriography.
- Comparison of invasive versus non-invasive strategies for coronary heart disease risk stratification.
Main Results:
- Coronary arteriography is indicated in incapacitating angina, high-risk unstable coronary syndromes, and acute ST-elevation myocardial infarction requiring intervention.
- Low-risk patients with atypical chest pain or stable angina may benefit from non-invasive testing, potentially avoiding arteriography.
- Current clinical practice shows less defined indications, with arteriography sometimes used as a first-line test for undifferentiated chest pain.
Conclusions:
- The indications for coronary arteriography in coronary heart disease require precise definition to optimize patient management.
- Non-invasive testing is appropriate for low-risk patients, reserving arteriography for specific high-risk scenarios.
- Appropriate use of coronary arteriography improves diagnostic accuracy and prognostic assessment in cardiovascular disease.
Abstract:
Recent advances in Medical Science and the thechnological improvements in the field of myocardial revascularisation, in surgical procedures and in percutaneous interventions, made attractive the initial option for invasive strategies in the management of coronary heart disease. For this reason, coronary arteriography is nowadays more often indicated. Some concepts in coronary heart disease have been reviewed, specially those related to acute coronary syndromes. Non-ST-segment elevation myocardial infarction (previously called non-Q wave myocardial infarction) and unstable angina are now considered "unstable acute coronary syndromes" and both have the same guidelines for management. The main indications for coronary arteriography as the first diagnostic tool are: 1) incapacitating angina, even in stable patients; 2) high-risk patients with unstable coronary syndromes (refractory angina, troponin elevation, new ST- segment deviations, cardiac failure and serious arrythmias); 3) patients with acute ST-elevation myocardial infarction that will be submitted to primary angioplasty or with hemodynamic instability or persistent ischemia. Low-risk patients (angina that promptly subsides after medication, no electrocardiographic or laboratorial changes or atypical chest pain) may be submitted to non-invasive testing for further risk stratification; if no ischemia is detected, coronary arteriography is not indicated and optimized medical treatment is perfectly admitted for a great number of patients. The indications of coronary arteriography for the diagnosis and prognosis of coronary heart disease are not well delimited in clinical practice, and this method is frequently used as the first tool in the investigation of chest pain, even when the characteristics of pain are not exactly those of angina. In this review, the authors discuss the main indications of coronary arteriography in the multiple clinical aspects of coronary heart disease and in the differential diagnosis of chest pain.
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