[Histopathologic aspects of degenerative and inflammatory disease of cornea]

Maintaining the transparency of the cornea is the most important factor in keeping its optical function. The purpose of this study is to evidentiate the structural changes suffered by the cornea during different ocular diseases, thus emphasizing the importance of applying, in due time, the correct therapy.

The studied material comes from two eyeballs, obtained as a result of enucleations performed on patients with painful primary glaucoma-absolute stage, secondary glaucoma-absolute stage. For comparison, a witness group represented by eyeballs without lesions was used. The material underwent histological techniques on paraffin and performed routine coloration.

The examination of the histological sections coming from the witness group revealed the known classical structure of the cornea. In glaucoma, the histological aspects are consequence of the ocular hypertension on the structures of the eyeball, depend on the stage of the disease, but are not influenced by the clinical form (open angle glaucoma and closed angle glaucoma).

The obtained results indicate dystrophic, circulatory and inflammatory lesions, that can lead to the loss of the transparency of the cornea, and thus to the loss of function of the visual organ. The aspects are important for establishing a precocious diagnosis and choosing the correct therapy.