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Synthetic metallo-porphyrins and selection criteria for PDT
1Institute for Chemical Research-Icechim, Chemical Analysis Department, Splaiul Independentei 202, Bucharest-77208, Romania. irma@pcnet.ro
Abstract:
The aim of this paper is to analyse the some aspects about the main selection criteria of some metallo-porphyrins for PDT; purity, solubility, singlet oxygen generation and photostability. Also, some clinical applications of some porphyrins are evaluated. The PDT effect of some metallo-porphyrins on Murine Lymphoma EL-4 cells (as experimental model for photodynamic therapy studies), on Herpes Simplex Virus, on human brain cells, in ophthalmology, are discussed in this review.
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