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Updated: Jul 28, 2026

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
The essential drugs concept is needed now more than ever
Mohga Kamal Smith1, Sophia Tickell
1OXFAM, 274 Banbury Road, Oxford OX2 7DZ, UK. mksmith@oxfam.org.uk
Summary
The essential medicines debate is back, focusing on access and the impact of intellectual property rights. The Essential Drugs List (EDL) remains a vital public health tool for guiding drug selection globally.
Area of Science:
- Public Health
- Health Policy
- Pharmaceutical Policy
Background:
- The concept of essential medicines, established in the 1970s-1980s, is resurfacing on the international health policy agenda.
- The Essential Drugs List (EDL) is a cornerstone of national drug policies in 146 countries, prioritizing public health relevance, efficacy, safety, and cost.
- Current concerns link the Trade-Related Aspects of Intellectual Property Rights (TRIPS) agreement to potential impacts on access to essential medicines.
Purpose of the Study:
- To review the concept of essential medicines within the evolving political landscape.
- To analyze the implications of international agreements on the accessibility of essential drugs.
- To advocate for continued support of the Essential Drugs List as a critical public policy instrument.
Main Methods:
- Literature review of the essential medicines concept and its historical context.
- Analysis of the current international health policy agenda and relevant agreements.
- Examination of the role and impact of the Essential Drugs List (EDL).
Main Results:
- The essential medicines debate has been reignited due to concerns over access, particularly in light of intellectual property agreements.
- The Essential Drugs List (EDL) is a widely adopted and crucial tool for ensuring rational drug selection based on public health needs.
- The political context surrounding essential medicines has shifted, necessitating a re-evaluation of access strategies.
Conclusions:
- The Essential Drugs List (EDL) is a fundamental public policy tool that requires sustained support in all nations.
- Addressing concerns related to intellectual property rights is essential for safeguarding access to essential medicines.
- Continued international dialogue and policy development are necessary to ensure equitable access to medicines globally.
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