Related Experiment Videos
Alzheimer's disease as a disconnection syndrome?
X Delbeuck1, M Van der Linden, F Collette
1Cognitive Psychopathology Unit, University of Geneva, Geneva, Switzerland. Xavier.Delbeuck@pse.unige.ch
Neuropsychology Review
|July 31, 2003
Abstract:
This paper reviews the growing amount of evidence supporting the hypothesis that Alzheimer's disease includes a disconnection syndrome. This evidence came mainly from neuropathological, electrophysiological, and neuroimaging studies. Moreover, a few recent neuropsychological studies have also explored the effects of a disconnection between cerebral areas on cognitive functioning. Finally, and more generally, the contribution of this interpretation to the understanding of Alzheimer's disease cognitive deficits is considered.