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Updated: Sep 20, 2026
Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
A case of primary B-cell type non-Hodgkin lymphoma originating in the iris
Kazuhiro Yamada1, Akira Hirata, Akira Kimura
1Department of Ophthalmology, Kumamoto University School of Medicine, Honjo, Kumamoto, Japan.
Purpose:
To report a case of primary malignant B-cell type non-Hodgkin lymphoma originating in the iris.
Design:
Interventional case report.
Methods:
An 83-year-old woman presented with anterior uveitis resulting from primary malignant lymphoma in the iris. Ultrasound biomicroscopy and indocyanine green angiography using a scanning laser ophthalmoscope showed abnormalities in the iris. Diagnostic biopsy of the iris revealed B-cell type non-Hodgkin lymphoma.
Result:
The patient was treated with radiotherapy, and the tumorous lesion resolved.
Conclusion:
Primary lymphoma localized in the iris only is rare. In this case, diagnostic biopsy and radiotherapy of the iris lymphoma provided good results.
