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Published on: February 3, 2014
Comparison of left ventricular function by echocardiogram in patients with Wilms' tumor treated with anthracyclines
Diana Iarussi1, Paolo Indolfi, Carlo Pisacane
1Cattedra di Cardiologia, Dipartimento di Scienze Cardio-Chirurgiche, Toraciche e Respiratorie, Naples, Italy. dianal.iarussi@unina2.it
Abstract:
The aim of this report was to evaluate late left ventricular function in survivors of Wilms' tumor and to compare patients treated with anthracyclines with those treated without anthracycline and with normal subjects. Wilms' tumor survivors treated without anthracycline had no myocardial abnormalities. A large percentage of patients treated with anthracycline presented with increased end-systolic wall stress. Results indicate that there is a high incidence of subclinical cardiovascular abnormalities in such patients.
