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Updated: Aug 18, 2026

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
Published on: September 11, 2012
Assessment of gastrointestinal involvement
P J Clements1, R Becvar, A A Drosos
1Division of Rheumatology/Medicine, Rm 32-59, 1000 Veteran Avenue, UCLA School of Medicine, Los Angeles, California, USA. pclements@mednet.ucla.edu
Abstract:
The purpose of this paper is to identify a list of clinical, laboratory and instrumental tools suitable to assess the presence of gastrointestinal involvement in SSc patients to be included in clinical investigational studies. The pertinent literature was reviewed to select those variables which have been demonstrated to be valid, reliable and feasible. A minimal core set of variables has been identified to be used in clinical investigation for the assessment of esophagus, stomach, small intestine, colon and anorectum involvement in scleroderma patients.
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