Primary lymphoma of the penis

Primary penile lymphoma is a rare neoplasm. We report a case of this unusual clinical manifestation. A 70-year-old male presented with a painless penile mass for 6 months. Penile ultrasonography disclosed a huge tumor over the left corpus cavernosum. Pathologic examination of needle biopsy showed diffuse, small and T-cell type malignant lymphoma. Whole-body computed tomography scan and bone marrow aspiration revealed no evidence of distant metastasis. We treated this patient with chemotherapy alone and achieved complete remission 2 months later. There was absence of tumor recurrence 20 months after treatment. We review the literature and discuss this uncommon lesion.