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Published on: August 16, 2018
Triterpene constituents from the leaves of Melicope indica
R Farruque1, R Chowdhury, M H Sohrab
1Phytochemical Research Laboratory, Department of Pharmacy, University of Dhaka, Bangladesh.
Abstract:
Phytochemical investigation of a petroleum ether extract of Melicope indica afforded two unusual pentacyclic triterpenes viz. neohop-13(18)-en-3alpha-ol (1) and fern-8(9)-en-3beta-ol (2) and the ubiquitous steroids, stigmasterol and sitosterol. The structures of 1 and 2 were independently elucidated on the basis of 2D NMR data and confirmed by comparison with those of related compounds. While compound 1 is a new natural product, this is the first report of occurrence of fern-8(9)-en-3beta-ol (2) from the genus Melicope.