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Hidradenitis suppurativa: pathogenesis and management.

D E M Slade1, B W Powell, P S Mortimer

  • 1Departments of Plastic and Reconstructive Surgery and Dermatology, St George's Hospital Medical School, London, UK. mail.dianaslade.co.uk

British Journal of Plastic Surgery
|August 2, 2003
PubMed
Summary

Hidradenitis suppurativa (HS) is a chronic skin condition causing painful abscesses. Early diagnosis and tailored treatments, including medical and surgical options, are crucial for managing this debilitating disease.

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Area of Science:

  • Dermatology
  • Pathogenesis of skin diseases

Background:

  • Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition characterized by recurrent abscesses, sinus tracts, and scarring.
  • It primarily affects apocrine gland-bearing skin and is linked to follicular occlusion, with potential genetic and hormonal influences.

Purpose of the Study:

  • To review the importance of early diagnosis, pathogenesis, etiology, and therapeutic evidence for Hidradenitis Suppurativa.
  • To clarify management strategies for HS based on disease severity and patient quality of life.

Main Methods:

  • This is a review article synthesizing current knowledge on Hidradenitis Suppurativa.
  • Evidence for medical and surgical therapies is evaluated.

Main Results:

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  • Early medical management with antibiotics can be effective for mild to moderate HS.
  • Radical excision of affected tissue is the definitive surgical treatment, while conservative procedures have a role in selected cases.
  • Lifestyle modifications, intralesional steroids, systemic retinoids, hormonal therapy, and radiotherapy are also discussed as management options.

Conclusions:

  • Effective management of HS requires tailored treatment plans, considering disease severity, patient quality of life, and interdisciplinary collaboration.
  • A cautious approach to surgical timing and planning is recommended to minimize recurrence rates.