Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Demystified...tissue microarray technology.

J Packeisen1, E Korsching, H Herbst

  • 1Department of Pathology, Klinikum Osnabrueck, 49076 Osnabrueck, Germany.

Molecular Pathology : MP
|August 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polypharmacy in Parkinson's disease: risks and benefits with little evidence.

Journal of neural transmission (Vienna, Austria : 1996)·2019
Same author

Initial free cortisol dynamics following blunt multiple trauma and traumatic brain injury: A clinical study.

The Journal of international medical research·2019
Same author

Prognostic impact of macrometastasis linear size in sentinel node biopsy for breast carcinoma.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same author

Insight into the incidence of acute aortic dissection in the German region of Berlin and Brandenburg.

International journal of cardiology·2017
Same author

Polymerase Chain Reaction Analysis of t(14;18) Junctional Regions in B-Cell Lymphomas.

Leukemia & lymphoma·2016
Same author

Epstein-Barr virus and carcinomas: rare association of the virus with gastric adenocarcinomas.

British journal of cancer·2016
Same journal

Development of molecular methods for the identification of aspergillus and emerging moulds in paraffin wax embedded tissue sections.

Molecular pathology : MP·2003
Same journal

Tempero-spatial dissociation between the expression of Fas and apoptosis after coronary occlusion.

Molecular pathology : MP·2003
Same journal

Inverse correlation between high level expression of cyclin E and proliferation index in transitional cell carcinoma of the bladder.

Molecular pathology : MP·2003
Same journal

Nuclear beta catenin as a potential prognostic and diagnostic marker in patients with colorectal cancer from Hong Kong.

Molecular pathology : MP·2003
Same journal

Increased cyclin D1 expression in cancer of the ampulla of Vater: relevance to nuclear beta catenin accumulation and k-ras gene mutation.

Molecular pathology : MP·2003
Same journal

Expression of the cell cycle regulatory proteins p34cdc2, p21waf1, and p53 in node negative invasive ductal breast carcinoma.

Molecular pathology : MP·2003
See all related articles

Tissue microarray (TMA) technology offers a high throughput approach for analyzing intact tissues. This method aids in understanding genomic alterations and gene expression for cancer diagnosis and treatment, with expanding applications.

Area of Science:

  • Biotechnology
  • Genomics
  • Cancer Research

Background:

  • High throughput methods have revolutionized biological research and diagnostics.
  • These methods generate vast datasets for analyzing genomic alterations and gene expression.
  • New tools are essential for interpreting this data, particularly in cancer research.

Purpose of the Study:

  • To review the technical aspects of Tissue Microarray (TMA) production.
  • To discuss current and potential future applications of TMA technology in research and diagnostics.
  • To highlight the role of TMAs in advancing cancer diagnosis and treatment.

Main Methods:

  • Tissue microarray (TMA) technology utilizes miniaturization and high throughput analysis of intact tissues.
  • TMA enables simultaneous analysis of multiple tissue samples.

Related Experiment Videos

  • This method facilitates large-scale molecular profiling.

    • Main Results:

    • TMAs have demonstrated significant potential and scientific value in numerous studies.
    • The application spectrum of TMAs is rapidly expanding.
    • TMAs are valuable for quality control, tissue banking, and pathologist education.

    Conclusions:

    • TMA technology is a powerful tool for high throughput tissue analysis.
    • Its applications extend beyond basic research into diagnostics and education.
    • TMAs are crucial for advancing cancer research and personalized medicine.