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Updated: Aug 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Published on: November 3, 2010

Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous

S L Lake1, H Lyon, K Tantisira

  • 1Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. 02115, USA. Stephen.Lake@channing.harvard.edu

Human Heredity
|August 2, 2003
PubMed
Summary

This study introduces a new statistical method for analyzing gene-environment interactions using haplotypes, which are combinations of genetic markers. The method effectively handles unobservable haplotype data for complex trait research.

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