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Vertical transmission of HIV in Rio de Janeiro, Brazil

Esaú Custódio João1, Maria Letícia Cruz, Jacqueline A Menezes

  • 1Infectious Diseases Department, Hospital dos Servidores do Estado, Rio de Janeiro, Brazil.

AIDS (London, England)
|August 2, 2003
PubMed

A cohort of 297 HIV-infected pregnant women was followed from January 1996 to December 2001. The overall transmission rate was 3.57% and remained constant over time. Low birth-weight was independently associated with a higher risk of vertical transmission (P=0.0072), whereas a longer duration of antiretroviral drugs during pregnancy was independently associated with a lower risk of transmission (P=0.0084). Further decreases in transmission should be obtained by initiating prophylaxis earlier in pregnancy.

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