Related Experiment Video
Updated: Sep 20, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
[Structural and functional changes of the myocardium after coronary artery bypass surgery in patients with
Abstract:
In patients with left ventricular end diastolic dimensions >5--< or =5.5 cm myocardial revascularization was associated with significant decreases of diastolic and systolic left ventricular dimensions in immediate postoperative period. This adaptational phenomenon was called passive reducing left ventricular remodeling. In patients with left ventricular end diastolic dimensions <5 and >5.5 cm revascularization was associated with dilation of the left ventricle. Restoration of myocardial blood supply produced overall positive effect on left ventricular functional capacity in patients with various severity of its postinfarction remodeling. Pathways of realization of this positive effect could be different.
Related Concept Videos
Heart Failure II: Pathophysiology
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Pathophysiology of Heart Failure
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Myocarditis I: Introduction
