Related Experiment Video
Updated: Sep 20, 2026

06:05
Assessing Urinary Tract Junction Obstruction Defects by Methylene Blue Dye Injection
Published on: October 12, 2017
Methylene blue: dangerous dye for neonates
Matthew Albert1, Marc S Lessin, Brian F Gilchrist
1Floating Hospital for Children and Tufts University School of Medicine, Boston, MA 02111, USA.
Journal of Pediatric Surgery
|August 2, 2003
Abstract:
Methylene blue is a basic dye commonly used in histologic microbiologic, and tissue staining. This report describes an instance of methylene blue toxicity in a premature neonate.
Insights
Methylene blue, a common dye, can cause toxicity in premature infants. This case report highlights a rare instance of adverse effects in a neonate.
Area of Science:
- Medical Toxicology
- Neonatal Medicine
- Histopathology
Background:
- Methylene blue is a widely utilized basic dye in various scientific disciplines, including histology, microbiology, and tissue staining.
- Its safety profile is generally well-established for standard applications.
Observation:
- This report details a specific case involving a premature neonate who experienced adverse effects.
- The neonate was exposed to methylene blue, leading to observable toxic symptoms.
Findings:
- The case demonstrates a rare instance of methylene blue toxicity in a neonatal patient.
- The observed toxicity underscores potential risks associated with methylene blue administration in vulnerable populations.
Implications:
- This case highlights the importance of careful consideration of dye administration in premature neonates.
- Further research may be warranted to understand the specific mechanisms and risk factors for methylene blue toxicity in neonates.
