Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Methylene blue: dangerous dye for neonates.

Matthew Albert1, Marc S Lessin, Brian F Gilchrist

  • 1Floating Hospital for Children and Tufts University School of Medicine, Boston, MA 02111, USA.

Journal of Pediatric Surgery
|August 2, 2003
PubMed
Summary

Methylene blue, a common dye, can cause toxicity in premature infants. This case report highlights a rare instance of adverse effects in a neonate.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-term Results of the North American Phase II Transanal Total Mesorectal Excision Multicenter Trial for Rectal Cancer.

Annals of surgery·2026
Same author

A Small RNA Derived From the 5' End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium.

Molecular microbiology·2025
Same author

Impact of neoadjuvant treatment on functional outcomes after transanal total mesorectal excision (taTME)-a case series.

Surgical endoscopy·2025
Same author

Idiopathic myointimal hyperplasia of the mesenteric veins-a report of two cases.

AME case reports·2024
Same author

Functional Outcomes After Transanal Total Mesorectal Excision (taTME) for Rectal Cancer: Results From the Phase II North American Multicenter Prospective Observational Trial.

Annals of surgery·2024
Same author

Multicenter phase II trial of transanal total mesorectal excision for rectal cancer: preliminary results.

Surgical endoscopy·2023

Area of Science:

  • Medical Toxicology
  • Neonatal Medicine
  • Histopathology

Background:

  • Methylene blue is a widely utilized basic dye in various scientific disciplines, including histology, microbiology, and tissue staining.
  • Its safety profile is generally well-established for standard applications.

Observation:

  • This report details a specific case involving a premature neonate who experienced adverse effects.
  • The neonate was exposed to methylene blue, leading to observable toxic symptoms.

Findings:

  • The case demonstrates a rare instance of methylene blue toxicity in a neonatal patient.
  • The observed toxicity underscores potential risks associated with methylene blue administration in vulnerable populations.

Implications:

  • This case highlights the importance of careful consideration of dye administration in premature neonates.
  • Further research may be warranted to understand the specific mechanisms and risk factors for methylene blue toxicity in neonates.

Related Experiment Videos