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Slit-Robo: neuronal guides signal in tumor angiogenesis
Zhao Jun Liu1, Meenhard Herlyn
1The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA. herlynm@wistar.upenn.edu
Cancer Cell
|August 2, 2003
Abstract:
Slit and Roundabout (Robo) are well-characterized for neuron and leukocyte guidance. Their governing roles have now been expanded to control tumor-endothelial cell communication and mediate tumor-induced angiogenesis.