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In vitro evaluation of three topical antimycotics against ring-worm fungi singly and in combination
M K Rai1, S K Upadhyay, S C Agrawal
1Department of Botany, Danielson College, Chhinwara.
Hindustan Antibiotics Bulletin
|August 1, 1992
Abstract:
Three antimycotic drugs, viz., Miconazole nitrate, Econazole nitrate and ciclopirox olamine were tested singly and in combination of miconazole nitrate and Econazole nitrate, Miconazole nitrate and Ciclopirox olamine, and Econazole nitrate and Ciclopirox olamine to evaluate in vitro efficacy against Trichophyton mentagrophytes and Macrosporum nanum. The best efficacy was shown by Ciclopirox olamine (MIC 0.78 microgram/ml) and a combination of Miconazole nitrate and Econazole nitrate (MIC 0.78 microgram/ml).